product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
CHIR 99021 trihydrochloride
catalog :
4953
quantity :
10 mg (also 50 mg)
price :
260 USD
more info or order :
citations: 4
Reference
Modic M, Grosch M, Rot G, Schirge S, Lepko T, Yamazaki T, et al. Cross-Regulation between TDP-43 and Paraspeckles Promotes Pluripotency-Differentiation Transition. Mol Cell. 2019;74:951-965.e13 pubmed publisher
WARD M, Gilad Y. A generally conserved response to hypoxia in iPSC-derived cardiomyocytes from humans and chimpanzees. elife. 2019;8: pubmed publisher
Montefiori L, Sobreira D, Sakabe N, Aneas I, Joslin A, Hansen G, et al. A promoter interaction map for cardiovascular disease genetics. elife. 2018;7: pubmed publisher
Judson R, Quarta M, Oudhoff M, Soliman H, Yi L, Chang C, et al. Inhibition of Methyltransferase Setd7 Allows the In Vitro Expansion of Myogenic Stem Cells with Improved Therapeutic Potential. Cell Stem Cell. 2018;22:177-190.e7 pubmed publisher
product information
brand :
Tocris
master code :
4953
SKU :
4953/10
product name :
CHIR 99021 trihydrochloride
description :
Hydrochloride salt of CHIR 99021 (Cat. No. 4423); selective GSK-3 inhibitor
target :
GSK-3 Inhibitors
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
98%
observed molecular weight :
574.72
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Hydrochloride salt of CHIR 99021 (Cat. No. 4423), a highly selective GSK-3 inhibitor.
catalog number base :
4953
product keywords :
CHIR99021 trihydrochloride glycogen synthase kinase 3 gsk-3 gsk-3a gsk-3alpha gsk-3 gsk-3b gsk-3beta gsk-3 inhibitors inhibits highly selective potent CT99021 Glycogen Synthase Kinase 3 Glycogen Synthase Kinase 4953,
extended description :
Hydrochloride salt of CHIR 99021 (Cat. No. 4423); selective GSK-3 inhibitor
chemical name text :
6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile trihydrochloride
formula :
C 22 H 18 Cl 2 N 8 .3HCl
formula text :
C22H18Cl2N8.3HCl
cas num :
1782235-14-6
2020 USD :
247
2021 USD :
260 USD
alt names :
CT99021
storage :
Store at -20°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK