SA 4503 dihydrochloride | Tocris Bioscience 4951/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SA 4503 dihydrochloride

catalog :

4951/10

quantity :

10 mg (also 50 mg)

price :

240 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Rennekamp A, Huang X, Wang Y, Patel S, Lorello P, Cade L, et al. ?1 receptor ligands control a switch between passive and active threat responses. Nat Chem Biol. 2016;12:552-8 pubmed publisher

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

4951

SKU :

4951/10

product name :

SA 4503 dihydrochloride

Description :

Selective 1 receptor agonist

target :

Sigma1 Receptor Agonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

441.43

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

SA 4503 dihydrochloride is a selective 1 receptor agonist (IC50 = 17.4 nM). Exhibits selectivity for 1 over 2 receptors. Inhibits angiotensin II-induced cardiomyocyte hypertrophy in vitro and attenuates myocardial hypertrophy in vivo . Enhances brain plasticity and sensorimotor function in a rat model of experimental stroke.

extended description :

Selective 1 receptor agonist

chemical name text :

1-[2-(3,4-Dimethoxyphenyl)ethyl]-4-(3-phenylpropyl)-piperazine dihydrochloride

formula :

C 23 H 32 N 2 O 2 .2HCl

formula text :

C23H32N2O2.2HCl

cas num :

165377-44-6

USD :

240 USD

product details :

Selective 1 receptor agonist

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage