PKI 166 hydrochloride | Tocris Bioscience 4941/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PKI 166 hydrochloride

catalog :

4941/10

quantity :

10 mg

price :

208 USD

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

4941

SKU :

4941/10

product name :

PKI 166 hydrochloride

description :

Potent EGFR-kinase inhibitor

target :

EGF Receptor Inhibitors

unit size :

10 mg

category :

Small Molecules

purity :

98%

storage :

Store at +4°C

observed molecular weight :

366.84

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

PKI 166 hydrochloride is a potent EGFR-kinase inhibitor (IC50 = 0.7 nM). Displays 3000-fold selectivity against a panel of serine/threonine kinases. Reduces metastasis and angiogenesis in a mouse model of pancreatic cancer. Antihypertensive and orally bioavailable.

product keywords :

187724-61-4 potent EGFR kinase inhibitors epidermal growth factor receptor tyrosine antiangiogenic antitumor antitumour inhibits PKI166 EGFR 4941,

extended description :

Potent EGFR-kinase inhibitor

chemical name text :

4-[4-[[(1R)-1-Phenylethyl]amino]-7H-pyrrolo[2,3-d]pyrimidin-6-yl]phenol hydrochloride

formula :

C20H18N4O.HCl

formula text :

C20H18N4O.HCl

cas num :

2230253-82-2

USD :

231

USD 2025 :

208 USD

product details :

Potent EGFR-kinase inhibitor