Sulfasalazine | Tocris Bioscience 4935/50 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Sulfasalazine

catalog :

4935/50

quantity :

50 mg

price :

67 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Shin S, Jeong B, Wall B, Li J, Shan N, Wen Y, et al. Participation of xCT in melanoma cell proliferation in vitro and tumorigenesis in vivo. Oncogenesis. 2018;7:86 pubmed publisher
CAMPBELL L, Richie C, Zhang Y, Heathward E, Coke L, Park E, et al. In vitro modeling of HIV proviral activity in microglia. FEBS J. 2017;: pubmed publisher
Yeligar S, Machida K, Tsukamoto H, Kalra V. Ethanol augments RANTES/CCL5 expression in rat liver sinusoidal endothelial cells and human endothelial cells via activation of NF-kappa B, HIF-1 alpha, and AP-1. J Immunol. 2009;183:5964-76 pubmed publisher

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

4935

SKU :

4935/50

product name :

Sulfasalazine

Description :

Inhibitor of NF- B activation; also inhibits SXC and folate transporter 1

target :

NFkB/IkB Inhibitors

category :

Small Molecules

unit size :

50 mg

purity :

97%

observed molecular weight :

398.39

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Sulfasalazine is an inhibitor of NF- B activation. Inhibits in vitro growth of the human pancreatic cancer cell lines MIA PaCa-2 and PANC-1, and induces apoptosis in glioblastoma cell lines. Also inhibits the cystine-glutamate antiporter, system Xc (SXC). Inhibitor of folate transporter 1 (SLC19A1); inhibits cellular uptake of Methotrexate (Cat. No. 1230) and cyclic dinucleotides, including 2 ,3 -cGAMP (Cat.No. 5945). Anti-inflammatory. Induces ferroptosis.

extended description :

Inhibitor of NF- B activation; also inhibits SXC and folate transporter 1

chemical name text :

5-[[4-(2-Pyridylsulfamoyl)phenyl]azo]salicylic acid

formula :

C 18 H 14 N 4 O 5 S

formula text :

C18H14N4O5S

cas num :

599-79-1

USD :

67 USD

product details :

Inhibitor of NF- B activation; also inhibits SXC and folate transporter 1

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage