AS 1892802 | Tocris Bioscience 4927 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

AS 1892802

catalog :

4927

quantity :

10 mg (also 50 mg)

price :

198 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

4927

SKU :

4927/10

product name :

AS 1892802

description :

Potent ROCK inhibitor; orally bioavailable

target :

Rho-kinase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

333.38

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent, ATP-competitive ROCK inhibitor (IC50 values are 52, 57 and 122 nM for human ROCK2, rat ROCK2 and human ROCK1 respectively by ELISA); also inhibits PKAC- and PRKX (IC50 values are 200 and 325 nM respectively). Exhibits analgesic effects in rat models of inflammatory (AIA) and noninflammatory (MIA) arthritic pain. Orally bioavailable.

catalog number base :

4927

product keywords :

AS1892802 rho kinases ROCK1 ROCK2 potent selective inhibitors inhibits ATP competitive pain analgesics analgesia chronic arthritis antiinflammatory MIA AIA orally bioavailable Rho-kinases 4927,

extended description :

Potent ROCK inhibitor; orally bioavailable

chemical name text :

N-[(1S)-2-Hydroxy-1-phenylethyl]-N -[4-(4-pyridinyl)phenyl]-urea

formula :

C 20 H 19 N 3 O 2

formula text :

C20H19N3O2

cas num :

928320-12-1

2020 USD :

220

2021 USD :

198 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage