UPF 648 | Tocris Bioscience 4926/10 product information

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product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

UPF 648

catalog :

4926/10

quantity :

10 mg

price :

403 USD

citations: 1

Reference
. ACNP 59th annual meeting: panels, mini-panels and study groups. Neuropsychopharmacology. 2020;45:1-67 pubmed publisher

product information

brand :

Tocris

MasterCode :

4926

SKU :

4926/10

product name :

UPF 648

target :

Hydroxylase Inhibitors

category :

Small Molecules

unit size :

10 mg

purity :

98%

observed molecular weight :

259.09

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

UPF 648 is a potent kynurenine 3-monooxygenase (kynurenine 3-hydroxylase; KMO) inhibitor (IC50 = 20 nM). Increases kynurenic acid levels, and decreases 3-HK and QUIN levels in cerebrum and liver of neonatal rodents. Neuroprotective in a Drosophila model of Huntington s disease.

extended description :

Potent kynurenine 3-monooxygenase (KMO) inhibitor

chemical name text :

(1S,2S)-2-(3,4-Dichlorobenzoyl)cyclopropanecarboxylic acid

formula :

C 11 H 8 Cl 2 O 3

formula text :

C11H8Cl2O3

cas num :

213400-34-1

USD :

403 USD

product details :

Potent kynurenine 3-monooxygenase (KMO) inhibitor

storage :

Store at +4°C