CEP 1347 | Tocris Bioscience 4924 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

CEP 1347

catalog :

4924

quantity :

1 mg

price :

288 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Prinz E, Aviram S, Aronheim A. WDR62 mediates TNFα-dependent JNK activation via TRAF2-MLK3 axis. Mol Biol Cell. 2018;29:2470-2480 pubmed publisher

product information

brand :

Tocris

master code :

4924

SKU :

4924/1

product name :

CEP 1347

description :

Inhibitor of JNK signaling

target :

JNK/c-jun Inhibitors

category :

Small Molecules

unit size :

1 mg

purity :

97%

observed molecular weight :

615.76

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Inhibitor of c-jun N-terminal kinase (JNK) signaling. Rescues motor neurons undergoing apoptosis (EC50 = 20 nM). Blocks A -induced cortical neuron apoptosis (EC50 ~51 nM). Does not inhibit ERK1 activity. Neuroprotective.

catalog number base :

4924

product keywords :

CEP1347 inhibitors inhibits JNK signaling Mitogen-Activated Protein Kinases c-Jun N-Terminal SAPKs Stress-Activated amyloidbeta amyloidb amyloid JNK/c-jun Amyloid Beta Peptides 4924,

extended description :

Inhibitor of JNK signaling

chemical name text :

(9S,10R,12R)-5-16-Bis[(ethylthio)methyl]-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3 ,2 ,1 -kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester

formula :

C 33 H 33 N 3 O 5 S 2

formula text :

C33H33N3O5S2

cas num :

156177-65-0

2020 USD :

276

2021 USD :

288 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage