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company name :
Tocris Bioscience
product type :
chemical
product name :
Methoxy-X04
catalog :
4920/10
quantity :
10 mg (also 50 mg)
price :
216 USD
more info or order :
citations: 41
Reference
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product information
brand :
Tocris, a Bio-Techne Brand
catalog number base :
4920
SKU :
4920/10
product name :
Methoxy-X04
Description :
Fluorescent amyloid detector; brain penetrant
target :
Fluorescent Amyloid B Probes
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
98%
observed molecular weight :
344.4
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Methoxy-X04 is a fluorescent amyloid (A ) probe for the detection and quantification of plaques, tangles and cerebrovascular amyloid. Methoxy-X04 displays high in vitro binding affinity (Ki = 26.8 nM); binds selectively to fibrillar -sheet deposits. Methoxy-X04 is a derivative of Congo Red (Cat. No. 5167). Methoxy-X04 can be used for in vivo A plaque labeling. Methoxy-X04 co-localizes with CD68+ phagosomes in plaque-associated Iba1+ microglia; and it labels molecularly distinct plaque-associated microglia populations. Brain penetrant. Em/Ex = 370/452 nm respectively.
extended description :
Fluorescent amyloid detector; brain penetrant
chemical name text :
4,4 -[(2-methoxy-1,4-phenylene)di-(1E)-2,1-ethenediyl]bisphenol
formula :
C 23 H 20 O 3
formula text :
C23H20O3
cas num :
863918-78-9
USD :
216 USD
product details :
Fluorescent amyloid detector; brain penetrant
storage :
Store at +4°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK