M 25 | Tocris Bioscience 4917 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

M 25

catalog :

4917

quantity :

10 mg (also 50 mg)

price :

214 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

4917

SKU :

4917/10

product name :

M 25

description :

Potent Smoothened (Smo) receptor antagonist

target :

Smoothened Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

379.5

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent Smoothened (Smo) receptor antagonist (IC50 = 5 nM). Inhibits the Hedgehog signaling pathway. Inhibits Shh induced Gli luciferase reporter activity in Shh-light 2 cells (IC50 = 5 nM). Antagonizes GSA-10 and SAG -mediated differentiation of the C3H10T1/2 cell line (IC50 values are 69 and 115 nM, respectively).

catalog number base :

4917

product keywords :

M25 Smoothened SMO antagonists inhibitors inhibits Hedgehog signaling pathway SAG Smoothened Receptors Hedgehog Signaling 4917,

extended description :

Potent Smoothened (Smo) receptor antagonist

chemical name text :

N-[[1-(2-Methoxyphenyl)-1H-indazol-5-yl]methyl]-2-propylpentanamide

formula :

C 23 H 29 N 3 O 2

formula text :

C23H29N3O2

2020 USD :

214

2021 USD :

214 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage