PF 04885614 | Tocris Bioscience 4916 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PF 04885614

catalog :

4916

quantity :

10 mg

price :

191 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

4916

SKU :

4916/10

product name :

PF 04885614

description :

Potent and selective NaV1.8 channel blocker; active in vivo

target :

Voltage-gated Sodium Channel Blockers

category :

Small Molecules

unit size :

10 mg

purity :

98%

observed molecular weight :

285.26

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent NaV1.8 inhibitor (IC50 = 53 nM for human NaV1.8 channel). Exhibits selectivity for hNaV1.8 over hNaV1.6, hNaV1.7, hNaV1.1, hNaV1.2 and hNaV1.5 (IC50 values are 4.2, 7.0, 11, 16 and 27 M respectively). Orally bioavailable.

catalog number base :

4916

product keywords :

PF04885614 NaV1.8 voltage gated sodium channel inhibitors inhibits potent selective in vivo efficacy antinociceptive analgesic Voltage-gated Sodium Channels 4916,

extended description :

Potent and selective NaV1.8 channel blocker; active in vivo

chemical name text :

1-Methyl-[1-[4-(4-trifluoromethoxy)phenyl]-imidazol-2-yl]-ethanamine

formula :

C 13 H 14 F 3 N 3 O

formula text :

C13H14F3N3O

cas num :

1480833-70-2

2020 USD :

185

2021 USD :

191 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage