PF 04885614 | Tocris Bioscience 4916/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PF 04885614

catalog :

4916/10

quantity :

10 mg

price :

241 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 4916 - PF 04885614 C13H14F3N3O CAS No. 1480833-70-2

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

4916

SKU :

4916/10

product name :

PF 04885614

description :

Potent and selective NaV1.8 channel blocker; active in vivo

target :

Voltage-gated Sodium Channel Blockers

unit size :

10 mg

category :

Small Molecules

purity :

98%

storage :

Store at +4°C

observed molecular weight :

285.26

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

PF 04885614 is a potent NaV1.8 inhibitor (IC50 = 53 nM for human NaV1.8 channel). Exhibits selectivity for hNaV1.8 over hNaV1.6, hNaV1.7, hNaV1.1, hNaV1.2 and hNaV1.5 (IC50 values are 4.2, 7.0, 11, 16 and 27 M respectively). Orally bioavailable.

product keywords :

PF04885614 NaV1.8 voltage gated sodium channel inhibitors inhibits potent selective in vivo efficacy antinociceptive analgesic Voltage-gated Sodium Channels 4916,

extended description :

Potent and selective NaV1.8 channel blocker; active in vivo

chemical name text :

1-Methyl-1-[4-(4-trifluoromethoxy-phenyl)-1H-imidazol-2-yl]-ethylamine

formula :

C13H14F3N3O

formula text :

C13H14F3N3O

cas num :

1480833-70-2

USD :

238

USD 2025 :

241 USD

product details :

Potent and selective NaV1.8 channel blocker; active in vivo

more info or order :

Tocris Bioscience product webpage