Jingzhaotoxin III | Tocris Bioscience 4913/100U product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Jingzhaotoxin III

catalog :

4913/100U

quantity :

100 ug

price :

455 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 4913 - Jingzhaotoxin III Asp-Gly-Glu-Cys-Gly-Gly-Phe-Trp-Trp-Lys-Cys-Gly-Arg-Gly-Lys-Pro-Pro-Cys-Cys-Lys-Gly-Tyr-Ala-Cys-Ser-Lys-Thr-Trp-Gly-Trp-Cys-Ala-Val-Glu-Ala-Pro (Disulfide bridges: 4-19, 11-24, 18-31) CAS No. 925463-91-8

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

4913

SKU :

4913/100U

product name :

Jingzhaotoxin III

Description :

Selective NaV1.5 channel blocker

target :

Voltage-gated Sodium Channel Blockers

category :

Peptides

unit size :

100 ug

purity :

95%

observed molecular weight :

3919.5

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

Jingzhaotoxin III is a selective blocker of NaV1.5 channels (IC50 = 348 nM); displays no effect on other isoforms, including NaV1.2, NaV1.4, NaV1.6 and NaV1.7. Thought to inhibit sodium channel activation by binding to the NaV1.5 S3-S4 linker of domain II. Selectively inhibits the activation of cardiac sodium channels, but has no effect on sodium channels in dorsal root ganglion neurons.

extended description :

Selective NaV1.5 channel blocker

formula :

C 174 H 241 N 47 O 46 S 6

formula text :

C174H241N47O46S6

cas num :

925463-91-8

USD :

455 USD

product details :

Selective NaV1.5 channel blocker

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage