GsMTx4 | Tocris Bioscience 4912 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

GsMTx4

catalog :

4912

quantity :

100 ug

price :

364 USD

more info or order :

Tocris Bioscience product webpage

citations: 5

Reference
Beaulieu Laroche L, Christin M, Donoghue A, Agosti F, Yousefpour N, Petitjean H, et al. TACAN Is an Ion Channel Involved in Sensing Mechanical Pain. Cell. 2020;180:956-967.e17 pubmed publisher
Sun W, Chi S, Li Y, Ling S, Tan Y, Xu Y, et al. The mechanosensitive Piezo1 channel is required for bone formation. elife. 2019;8: pubmed publisher
Wong T, Juang W, Tsai C, Tseng C, Lee W, Chang S, et al. Mechanical Stretching Simulates Cardiac Physiology and Pathology through Mechanosensor Piezo1. J Clin Med. 2018;7: pubmed publisher
Agbani E, Williams C, Li Y, van den Bosch M, Moore S, Mauroux A, et al. Aquaporin-1 regulates platelet procoagulant membrane dynamics and in vivo thrombosis. JCI Insight. 2018;3: pubmed publisher
dela Paz N, Frangos J. Yoda1-induced phosphorylation of Akt and ERK1/2 does not require Piezo1 activation. Biochem Biophys Res Commun. 2018;497:220-225 pubmed publisher

product information

brand :

Tocris

master code :

4912

SKU :

4912/100U

product name :

GsMTx4

description :

TRPC1 and TRPC6 blocker; inhibits mechanosensitive ion channels

target :

TRPC Channel Blockers

category :

Peptides

unit size :

100 ug

observed molecular weight :

4095.86

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

TRPC1 and TRPC6 blocker. Also blocks stretch-activated cation channels in astrocytes, cardiac cells, and smooth and skeletal muscle cells. Also inhibits TACAN, a mechanosensitive ion channel involved in the pain response.

catalog number base :

4912

product keywords :

TRPC transient receptor potential TRPC1 and TRPC6 mechanosensitive ion channels MSCs blockers blocks inhibits inhibitors venoms TACAN pain TMEM120A TMEM TRPC Piezo Channels Other Channel Modulators 4912,

extended description :

TRPC1 and TRPC6 blocker; inhibits mechanosensitive ion channels

formula :

C 185 H 273 N 49 O 45 S 6

formula text :

C185H273N49O45S6

2020 USD :

346

2021 USD :

364 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage