GaTx2 | Tocris Bioscience 4911 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

GaTx2

catalog :

4911

quantity :

100 ug

price :

356 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Nighot P, Leung L, Ma T. Chloride channel ClC- 2 enhances intestinal epithelial tight junction barrier function via regulation of caveolin-1 and caveolar trafficking of occludin. Exp Cell Res. 2017;352:113-122 pubmed publisher

product information

brand :

Tocris

master code :

4911

SKU :

4911/100U

product name :

GaTx2

description :

High affinity, selective ClC-2 blocker; inhibits slow-gating

target :

Other Chloride Channel Blockers

category :

Peptides

unit size :

100 ug

observed molecular weight :

3192.54

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

Very high affinity ClC-2 blocker (apparent KD ~ 50 pM). Slows ClC-2 activation and inhibits slow-gating but does not inhibit open ClC-2 channels. Selective for ClC-2 over other ClC family members (ClC-0, ClC-1, ClC-3 and ClC-4), CFTR, GABAC, CaCC and KV1.2.

catalog number base :

4911

product keywords :

high affinity ClC-2 blockers chloride channels selective slow gating venoms Leiuropeptide II Other Chloride Channels 4911,

extended description :

High affinity, selective ClC-2 blocker; inhibits slow-gating

formula :

C 125 H 199 N 39 O 47 S 6

formula text :

C125H199N39O47S6

cas num :

194665-85-5

2020 USD :

349

2021 USD :

356 USD

alt names :

Leiuropeptide II

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage