NU 9056 | Tocris Bioscience 4903 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

NU 9056

catalog :

4903

quantity :

10 mg

price :

162 USD

more info or order :

Tocris Bioscience product webpage

citations: 6

Reference
Narkaj K, Stefanelli G, Wahdan M, Azam A, Ramzan F, Steininger C, et al. Blocking H2A.Z Incorporation via Tip60 Inhibition Promotes Systems Consolidation of Fear Memory in Mice. Eneuro. 2018;5: pubmed publisher
Scaglione A, Patzig J, Liang J, Frawley R, Bok J, Mela A, et al. PRMT5-mediated regulation of developmental myelination. Nat Commun. 2018;9:2840 pubmed publisher
Ho C, Bon C, Ng Y, Herr D, Wu J, Lin T, et al. Expression of DHA-Metabolizing Enzyme Alox15 is Regulated by Selective Histone Acetylation in Neuroblastoma Cells. Neurochem Res. 2018;43:540-555 pubmed publisher
Parira T, Figueroa G, Laverde A, Casteleiro G, Gomez Hernandez M, FERNANDEZ LIMA F, et al. Novel detection of post-translational modifications in human monocyte-derived dendritic cells after chronic alcohol exposure: Role of inflammation regulator H4K12ac. Sci Rep. 2017;7:11236 pubmed publisher
Bakshi K, Ranjitha B, Dubey S, Jagannadham J, Jaiswal B, Gupta A. Novel complex of HAT protein TIP60 and nuclear receptor PXR promotes cell migration and adhesion. Sci Rep. 2017;7:3635 pubmed publisher
Rollins M, Huard S, Morettin A, Takuski J, Pham T, Fullerton M, et al. Lysine acetyltransferase NuA4 and acetyl-CoA regulate glucose-deprived stress granule formation in Saccharomyces cerevisiae. PLoS Genet. 2017;13:e1006626 pubmed publisher

product information

brand :

Tocris

master code :

4903

SKU :

4903/10

product name :

NU 9056

description :

Inhibitor of KAT5 (Tip60)

target :

Histone Acetyltransferase Inhibitors

category :

Small Molecules

unit size :

10 mg

observed molecular weight :

232.37

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Selective KAT5 (Tip60) histone acetyltransferase inhibitor (IC50 values are 2, 60, 36, and 100 M for KAT5, p300, pCAF and GCN5, respectively). Inhibits protein acetylation in prostate cancer cell lines and blocks DNA damage response. Decreases proliferation of LNCaP cells; induces apoptosis via caspase activation.

catalog number base :

4903

product keywords :

NU9056 KAT5 Tip60 histone acetyltransferase HAT inhibitors inhibits acetylation dna damage proliferation apoptosis caspase Histone Acetyltransferases Post-translational Modifications 4903,

extended description :

Inhibitor of KAT5 (Tip60)

chemical name text :

5-(1,2-Thiazol-5-yldisulfanyl)-1,2-thiazole

formula :

C 6 H 4 N 2 S 4

formula text :

C6H4N2S4

cas num :

1450644-28-6

2020 USD :

155

2021 USD :

162 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage