chemical

ML 120B dihydrochloride

4899

10 mg (also 50 mg)

342 USD

4899

4899/10

ML 120B dihydrochloride

Novel IKK2-selective inhibitor

IkB Kinase Inhibitors

Small Molecules

10 mg (also 50 mg)

98%

439.72

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Novel, ATP-competitive IKK2-selective inhibitor (IC50 = 60 nM at 50 M ATP). Exhibits no inhibition at IKK1 (EC50 100 M), IKK (EC50 100 M) or a panel of 28 other kinases (EC50 50 M). Exhibits antitumor activity in lymphoma-bearing SCID mice. Demonstrates synergistic cytotoxic effects with vincristine (Cat. No. 1257).

4899

ML120B dihydrochloride IKK2 inhibitor ikk-2 NF-kappaB NF-kB NF- I B IkappaB Kinases Nuclear Factor Kappa B potent selective inhibitors inhibits inhibitory factor-kappab αb kinases NF-kB/IkB IkB Kinase 4899,

Novel IKK2-selective inhibitor

N-(6-Chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-2-methyl-3-pyridinecarboxamide dihydrochloride

C 19 H 15 ClN 4 O 2 .2HCl

C19H15ClN4O2.2HCl

1782573-78-7

332

342 USD

Store at -20°C