ML 120B dihydrochloride | Tocris Bioscience 4899/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ML 120B dihydrochloride

catalog :

4899/10

quantity :

10 mg (also 50 mg)

price :

424 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

4899

SKU :

4899/10

product name :

ML 120B dihydrochloride

Description :

Novel IKK2-selective inhibitor

target :

IkB Kinase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

439.72

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

ML 120B dihydrochloride is a novel, ATP-competitive IKK2-selective inhibitor (IC50 = 60 nM at 50 M ATP). Exhibits no inhibition at IKK1 (EC50 100 M), IKK (EC50 100 M) or a panel of 28 other kinases (EC50 50 M). Exhibits antitumor activity in lymphoma-bearing SCID mice. Demonstrates synergistic cytotoxic effects with vincristine (Cat. No. 1257).

extended description :

Novel IKK2-selective inhibitor

chemical name text :

N-(6-Chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-2-methyl-3-pyridinecarboxamide dihydrochloride

formula :

C 19 H 15 ClN 4 O 2 .2HCl

formula text :

C19H15ClN4O2.2HCl

cas num :

1782573-78-7

USD :

424 USD

product details :

Novel IKK2-selective inhibitor

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage