ML 299 | Tocris Bioscience 4894/2 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ML 299

catalog :

4894/2

quantity :

2 mg

price :

164 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 4894 - ML 299 C23H26BrFN4O2 CAS No. 1426916-00-8

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

4894

SKU :

4894/2

product name :

ML 299

description :

Potent inhibitor of PLD1 and PLD2; CNS penetrant

target :

Phospholipase Inhibitors

unit size :

2 mg

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

489.39

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

ML 299 is a selective allosteric modulator and potent inhibitor of phospholipases D1 and D2 (IC50 values are 6 and 12 nM, respectively). ML 299 decreases invasive migration in glioblastoma cells and increases caspase 3/7 activity in serum-free conditions. ML 299 is non-cytotoxic, active in vivo and CNS penetrant.

product keywords :

ML299 potent inhibitor inhibitors inhibition phospholipaseD phospholipaseD2 phospholipases allosteric modulator PLD1 PLD2 selective Phospholipases 4894,

extended description :

Potent inhibitor of PLD1 and PLD2; CNS penetrant

chemical name text :

4-Bromo-N-[(1S)-2-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-8-yl]-1-methylethyl]benzamide

formula :

C23H26BrFN4O2

formula text :

C23H26BrFN4O2

cas num :

1426916-00-8

USD :

182

USD 2025 :

164 USD

product details :

Potent inhibitor of PLD1 and PLD2; CNS penetrant

more info or order :

Tocris Bioscience product webpage