R 1530 | Tocris Bioscience 4885 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

R 1530

catalog :

4885

quantity :

10 mg (also 50 mg)

price :

215 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

4885

SKU :

4885/10

product name :

R 1530

description :

Multi-RTK inhibitor; inhibits angiogenesis

target :

Additional RTK Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

356.78

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Multi-kinase inhibitor. Exhibits inhibitory activity against Chk2, KDR, FGFR, Aurora A kinase and Cdk2 (IC50 values are 24, 34, 50, 58 and 88 nM respectively). Also binds VEGFR-2, FGFR1 and PDGFR (Kd values are 0.015, 0.061 and 0.088 M respectively). Displays antiproliferative activity in vitro ; inhibits mitosis and angiogenesis. Orally bioavailable.

catalog number base :

4885

product keywords :

R1530 multi-RTK inhibitors inhibits receptor tyrosine kinases Chk2 KDR FGFR Aurora A Cdk2 VEGFR-2 FGFR1 PDGFRb PDGFRbeta PDGFR angiogenesis antiangiogenics Other RTKs Antiangiogenics 4885,

extended description :

Multi-RTK inhibitor; inhibits angiogenesis

chemical name text :

5-(2-Chlorophenyl)-7-fluoro-1,2-dihydro-8-methoxy-3-methylpyrazolo[3,4-b][1,4]benzodiazepine

formula :

C 18 H 14 ClFN 4 O

formula text :

C18H14ClFN4O

cas num :

882531-87-5

2020 USD :

215

2021 USD :

215 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage