CU CPT 22 | Tocris Bioscience 4884 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

CU CPT 22

catalog :

4884

quantity :

10 mg (also 50 mg)

price :

266 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Ahn H, Han B, Kim J, Kang S, Kim P, Jang K, et al. Nonsaponin fraction of Korean Red Ginseng attenuates cytokine production via inhibition of TLR4 expression. J Ginseng Res. 2019;43:291-299 pubmed publisher
Ghonime M, Mitra S, Eldomany R, Wewers M, Gavrilin M. Inflammasome priming is similar for francisella species that differentially induce inflammasome activation. PLoS ONE. 2015;10:e0127278 pubmed publisher

product information

brand :

Tocris

master code :

4884

SKU :

4884/10

product name :

CU CPT 22

description :

Selective TLR1/2 inhibitor

target :

Toll-like Receptor Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

362.37

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Selective toll-like receptor 1/2 (TLR1/2) inhibitor (IC50 = 0.58 M). Exhibits no activity at TLR2/TLR6, TLR3, TLR4 and TLR7 or a panel of 10 representative kinases. Inhibits the release of proinflammatory cytokines TNF- and IL-1 .

catalog number base :

4884

product keywords :

CUCPT22 toll-like receptors inhibitors inhibits selective proinflammatory cytokines TLR TLR1 TLR2 TRL1/TLR2 Toll-like Receptors 4884,

extended description :

Selective TLR1/2 inhibitor

chemical name text :

3,4,6-Trihydroxy-2-methoxy-5-oxo-5H-benzocycloheptene-8-carboxylic acid hexyl ester

formula :

C 19 H 22 O 7

formula text :

C19H22O7

cas num :

1416324-85-0

2020 USD :

258

2021 USD :

266 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage