product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
ML 281
catalog :
4880/10
quantity :
10 mg (also 50 mg)
price :
189 USD
more info or order :
Tocris Bioscience product webpage
citations: 1
Reference
Moser R, Annis J, Nikolova O, Whatcott C, Gurley K, Mendez E, et al. Pharmacologic Targeting of TFIIH Suppresses KRAS-Mutant Pancreatic Ductal Adenocarcinoma and Synergizes with TRAIL. Cancer Res. 2022;82:3375-3393 pubmed publisher
product information
brand :
Tocris
catalog number base :
4880
SKU :
4880/10
product name :
ML 281
units size :
10 mg (also 50 mg)
description :
STK33 inhibitor
target :
Other Kinase Inhibitors
category :
Small Molecules
purity :
98%
observed molecular weight :
389.47
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
ML 281 is an inhibitor of the serine/threonine kinase STK33 (IC50 = 14 nM). Exhibits 700-fold selectivity for STK33 over the structurally related protein kinase A (PKA); also exhibits 550-fold selectivity over Aurora kinase B.
top caption :
STK33 inhibitor
extended description :
STK33 inhibitor
chemical name text :
N-[2-(3,4-Dihydro-3-oxo-2-quinoxalinyl)-4-(1-methylethyl)phenyl]-2-thiophenecarboxamide
formula :
C22H19N3O2S
formula text :
C22H19N3O2S
cas num :
1404437-62-2
USD :
189 USD
product details :
STK33 inhibitor
storage :
Store at +4°C
more info or order :
Tocris Bioscience product webpage
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK