This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Tocris Bioscience
product type :
chemical
product name :
H2L 5765834
catalog :
4870/10
quantity :
10 mg (also 50 mg)
price :
272 USD
citations: 2
Reference
Garofano K, Rashid K, Smith M, Brantner C, Suwunnakorn S, Diemert D, et al. Prostate cancer cell-platelet bidirectional signaling promotes calcium mobilization, invasion and apoptotic resistance via distinct receptor-ligand pairs. Sci Rep. 2023;13:2864 pubmed publisher
Kittaka H, Uchida K, Fukuta N, Tominaga M. Lysophosphatidic acid-induced itch is mediated by signalling of LPA5 receptor, phospholipase D and TRPA1/TRPV1. J Physiol. 2017;595:2681-2698 pubmed publisher
product information
brand :
Tocris, a Bio-Techne Brand
catalog number base :
4870
SKU :
4870/10
product name :
H2L 5765834
Description :
LPA1,3,5 antagonist
target :
Lysophosphatidic Acid (LPA) Receptor Antagonists
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
99%
observed molecular weight :
404.33
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
H2L 5765834 is an antagonist of the lysophosphatidic acid receptors LPA1, LPA5 and LPA3 (IC50 values are 94, 463 and 752 nM respectively). Exhibits no effect at LPA2 or LPA4 receptors.
extended description :
LPA1,3,5 antagonist
chemical name text :
2,3-Dihydro-2-[3-(4-nitrophenoxy)phenyl]-1,3-dioxo-1H-isoindole-5-carboxylic acid
formula :
C 21 H 12 N 2 O 7
formula text :
C21H12N2O7
cas num :
420841-84-5
USD :
272 USD
product details :
LPA1,3,5 antagonist
storage :
Store at +4°C
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK