ML 193 | Tocris Bioscience 4860 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ML 193

catalog :

4860

quantity :

10 mg

price :

270 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Alharris E, Singh N, Nagarkatti P, Nagarkatti M. Role of miRNA in the regulation of cannabidiol-mediated apoptosis in neuroblastoma cells. Oncotarget. 2019;10:45-59 pubmed publisher
Saliba S, Jauch H, Gargouri B, Keil A, Hurrle T, Volz N, et al. Anti-neuroinflammatory effects of GPR55 antagonists in LPS-activated primary microglial cells. J Neuroinflammation. 2018;15:322 pubmed publisher
Zong L, Chen J, Zhu Y, Zhao H. Progressive age-dependence and frequency difference in the effect of gap junctions on active cochlear amplification and hearing. Biochem Biophys Res Commun. 2017;489:223-227 pubmed publisher

product information

brand :

Tocris

master code :

4860

SKU :

4860/10

product name :

ML 193

description :

Potent, selective GPR55 antagonist

target :

GPR55 Receptor Antagonists

category :

Small Molecules

unit size :

10 mg

purity :

98%

observed molecular weight :

527.59

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Selective GPR55 antagonist (IC50 = 221 nM). Exhibits 27-, 145- and 145-fold selectivity for GPR55 over CB1, GPR35 and CB2, respectively. Inhibits ERK signaling in vitro .

catalog number base :

4860

product keywords :

ML193 CID1261822 GPR55 agonists potent selective agonism cannabinoids CID 1261822 GPR55 4860,

extended description :

Potent, selective GPR55 antagonist

chemical name text :

N-[4-[[(3,4-Dimethyl-5-isoxazolyl)amino]sulfonyl]phenyl]-6,8-dimethyl-2-(2-pyridinyl)-4-quinolinecarboxamide

formula :

C 28 H 25 N 5 O 4 S

formula text :

C28H25N5O4S

cas num :

713121-80-3

2020 USD :

259

2021 USD :

270 USD

alt names :

CID 1261822

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage