WIKI4 | Tocris Bioscience 4855 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

WIKI4

catalog :

4855

quantity :

25 mg

price :

480 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Yung T, Poon F, Liang M, Coquenlorge S, McGaugh E, Hui C, et al. Sufu- and Spop-mediated downregulation of Hedgehog signaling promotes beta cell differentiation through organ-specific niche signals. Nat Commun. 2019;10:4647 pubmed publisher

product information

brand :

Tocris

master code :

4855

SKU :

4855/25

product name :

WIKI4

description :

Potent tankyrase inhibitor

target :

Tankyrase Inhibitors

category :

Small Molecules

unit size :

25 mg

purity :

98%

observed molecular weight :

521.59

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Inhibitor of Wnt/ -catenin signaling (EC50 ~ 75 nM). Inhibits auto-ADP-ribosylation of tankyrase 2 (TNKS2) (IC50 ~15 nM); prevents the ubiquitination and degradation of axin.

catalog number base :

4855

product keywords :

Wnt signaling signalling inhibitors inhibits b-catenin beta-catenin -catenin tankyrase TNKS2 Poly(ADP-ribose) Polymerase Stem Cell Signaling Tankyrase 4855,

extended description :

Potent tankyrase inhibitor

chemical name text :

2-[3-[[4-(4-Methoxyphenyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]propyl]-1H-benz[de]isoquinoline-1,3(2H)-dione

formula :

C 29 H 23 N 5 O 3 S

formula text :

C29H23N5O3S

cas num :

838818-26-1

2020 USD :

457

2021 USD :

480 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage