ML 00253764 hydrochloride | Tocris Bioscience 4854/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ML 00253764 hydrochloride

catalog :

4854/10

quantity :

10 mg (also 50 mg)

price :

312 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

4854

SKU :

4854/10

product name :

ML 00253764 hydrochloride

Description :

Melanocortin MC4 receptor antagonist; brain penetrant

target :

Melanocortin Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

413.71

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

ML 00253764 hydrochloride is a non-peptide, melanocortin MC4 receptor antagonist (IC50 values are 320, 810 and 2120 nM for MC4, MC3 and MC5 receptors respectively). Decreases cAMP accumulation in HEK-293 cells expressing the MC4 receptor. Increases food intake and reduces loss of lean body mass in tumor bearing mice. Brain penetrant.

extended description :

Melanocortin MC4 receptor antagonist; brain penetrant

chemical name text :

2-[2-[2-(5-Bromo-2-methoxyphenyl)ethyl]-3-fluorophenyl]-4,5-dihydro-2-1H-imidazole hydrochloride

formula :

C 18 H 18 BrFN 2 O.HCl

formula text :

C18H18BrFN2O.HCl

cas num :

1706524-94-8

USD :

312 USD

product details :

Melanocortin MC4 receptor antagonist; brain penetrant

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage