HJC 0350 | Tocris Bioscience 4844/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

HJC 0350

catalog :

4844/10

quantity :

10 mg (also 50 mg)

price :

208 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Goode D, Molliver D. Regulation of Mitochondrial Function by Epac2 Contributes to Acute Inflammatory Hyperalgesia. J Neurosci. 2021;41:2883-2898 pubmed publisher
Ramos C, Lin C, Liu X, Antonetti D. The EPAC-Rap1 pathway prevents and reverses cytokine-induced retinal vascular permeability. J Biol Chem. 2018;293:717-730 pubmed publisher

image

image 1 :

Cat.No. 4844 - HJC 0350 C15H19NO2S CAS No. 885434-70-8

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

4844

SKU :

4844/10

product name :

HJC 0350

description :

Selective Epac2 inhibitor

target :

EPAC Inhibitors

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at +4°C

observed molecular weight :

277.38

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

HJC 0350 is a selective Epac2 inhibitor (IC50 = 0.3 M). Displays no effect on Epac1. Blocks stimulation of the Epac2-FL FRET sensor in HEK293 cells.

product keywords :

HJC0350 EPAC EPAC2 epacs antagonists inhibitors inhibits exchange proteins directly activated by cAMP Rap guanine nucleotide exchange factor 4 RAPGEF4 cAMP GEFI EPAC 4844,

extended description :

Selective Epac2 inhibitor

chemical name text :

2,4-Dimethyl-1-[(2,4,6-trimethylphenyl)sulfonyl]-1H-pyrrole

formula :

C15H19NO2S

formula text :

C15H19NO2S

cas num :

885434-70-8

USD :

205

USD 2025 :

208 USD

product details :

Selective Epac2 inhibitor

more info or order :

Tocris Bioscience product webpage