AZD 3988 | Tocris Bioscience 4837 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

AZD 3988

catalog :

4837

quantity :

10 mg (also 50 mg)

price :

368 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Mahoney C, Pirman D, Chubukov V, Sleger T, Hayes S, Fan Z, et al. A chemical biology screen identifies a vulnerability of neuroendocrine cancer cells to SQLE inhibition. Nat Commun. 2019;10:96 pubmed publisher

product information

brand :

Tocris

master code :

4837

SKU :

4837/10

product name :

AZD 3988

description :

Potent and selective DGAT-1 inhibitor

target :

Acyltransferase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

456.44

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective diacylglycerol acyltransferase (DGAT-1) inhibitor (IC50 = 0.6 nM). Exhibits selectivity for DGAT-1 over DGAT-2, Kv11.1 (hERG) and cytochrome P450 enzymes. Suppresses triacylglyceride (TAG) plasma excursion and adipose tissue TAG synthesis in rats. Reduces body weight of diet-induced obese rats. Cell permeable and orally bioavailable.

catalog number base :

4837

product keywords :

AZD3988 potent selective diacylglycerol transferases DGAT1 inhibitors inhibits obesity orally bioavailable cell permeable Diacylglycerol O-Acyltransferase 4837,

extended description :

Potent and selective DGAT-1 inhibitor

chemical name text :

trans-4-[-[[[5-[(3,4-Difluorophenyl)amino]-1,3,4-oxadiazol-2-yl]carbonyl]amino]phenyl]cyclohexaneacetic acid

formula :

C 23 H 22 F 2 N 4 O 4

formula text :

C23H22F2N4O4

cas num :

892489-52-0

2020 USD :

353

2021 USD :

368 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage