GPP 78 hydrochloride | Tocris Bioscience 4835 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

GPP 78 hydrochloride

catalog :

4835

quantity :

10 mg (also 50 mg)

price :

236 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Fons N, Sundaram R, Breuer G, Peng S, McLean R, Kalathil A, et al. PPM1D mutations silence NAPRT gene expression and confer NAMPT inhibitor sensitivity in glioma. Nat Commun. 2019;10:3790 pubmed publisher

product information

brand :

Tocris

master code :

4835

SKU :

4835/10

product name :

GPP 78 hydrochloride

description :

NAMPT inhibitor; also induces autophagy

target :

NAMPT Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

476.01

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Inhibitor of nicotinamide phosphoribosyltransferase (NAMPT); potently depletes NAD levels and exhibits cytotoxicity in vitro (IC50 values are 3.0 and 3.8 nM respectively). Also shown to induce autophagy in neuroblastoma cells.

catalog number base :

4835

product keywords :

GPP78 hydrochloride NMPRTase NAMPT NAD nicotinamide phosphoribosyltransferase inhibitors inhibits autophagy induces inducers Autophagy NAMPT 4835, PBEF inhibitors, visfatin inhibitors, nicotinamide phosphoribosyltransferase

extended description :

NAMPT inhibitor; also induces autophagy

chemical name text :

N-[1,1 -Biphenyl]-2-yl-4-(3-pyridinyl)-1H,1,2,3-triazole-1-octanamide hydrochloride

formula :

C 27 H 29 N 5 O.HCl

formula text :

C27H29N5O.HCl

2020 USD :

236

2021 USD :

236 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage