TC ASK 10 | Tocris Bioscience 4825/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TC ASK 10

catalog :

4825/10

quantity :

10 mg (also 50 mg)

price :

299 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

4825

SKU :

4825/10

rank :

0.061

product name :

TC ASK 10

description :

Potent and selective ASK1 inhibitor; orally bioavailable

target :

Other ER Stress/UPR Inhibitors

category :

Small Molecules

sizes available :

10 mg (also 50 mg)

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

TC ASK 10 is a potent ASK1 inhibitor (IC50 = 14 nM); displays selectivity for ASK1 over other kinases including ASK2 (IC50 = 0.51 M), MEKK1, TAK1, IKK , ERK1, JNK1, p38 , GSK-3 , PKC and B-raf (IC50 values are 10 M). Blocks downstream JNK1/p38 phosphorylation in cells. Orally bioavailable.

extended description :

Potent and selective ASK1 inhibitor; orally bioavailable

chemical name text :

4-(1,1-Dimethylethyl)-N-[6-(1H-imidazol-1-yl)imidazo[1,2-a]pyridin-2-yl]benzamide dihydrochloride

formula :

C 21 H 21 N 5 O.2HCl

formula text :

C21H21N5O.2HCl

cas num :

1005775-56-3

USD :

299 USD

product details :

Potent and selective ASK1 inhibitor; orally bioavailable

storage :

Store the unopened product at room temperature. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage