PF 05212384 | Tocris Bioscience 4823 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PF 05212384

catalog :

4823

quantity :

10 mg

price :

275 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

4823

SKU :

4823/10

product name :

PF 05212384

description :

Potent and selective dual PI 3-K/mTOR inhibitor

target :

PI 3-Kinase Inhibitors

category :

Small Molecules

unit size :

10 mg

purity :

98%

observed molecular weight :

615.73

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective dual inhibitor of PI 3-kinase/mTOR (IC50 values are 0.4, 1.6 and 5.4 nM for PI 3-K , mTOR and PI 3-K respectively). Exhibits selectivity over 234 other protein kinases (IC50 10 M). Potently inhibits tumor cell growth in 37 different tumor cell lines (IC50 100 nM). Also exhibits antitumor activity in MDA-361, HCT-116, H1975 and U87MG xenograft models.

catalog number base :

4823

product keywords :

PF05212384 antitumor antitumour PI3-K phosphoinositide 3-kinases mTOR mammalian target of rapamycin inhibitors inhibits PKI587 Pfizer PKI-587 Gedatolisib PI 3-Kinase mTOR 4823,

extended description :

Potent and selective dual PI 3-K/mTOR inhibitor

chemical name text :

N-[4-[[4-(Dimethylamino)-1-piperidinyl]carbonyl]phenyl]-N -[4-(4,6-di-4-morpholinyl-1,3,5-triazin-2-yl)phenyl]urea

formula :

C 32 H 41 N 9 O 4

formula text :

C32H41N9O4

cas num :

1197160-78-3

2020 USD :

275

2021 USD :

275 USD

alt names :

PKI-587, Gedatolisib

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage