chemical

CRANAD 2

4803/10

10 mg

346 USD

4803

4803/10

CRANAD 2

10 mg

Near-infrared probe that detects A 40 aggregates. Used for: amyloid- detection in vitro and in vivo. Application: fluorescence microscopy, epifluorescence microscopy

Fluorescent Amyloid B Probes

Small Molecules

98%

410.26

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Key information : CRANAD 2 is a curcumin derivatized near-infrared probe that binds to A 40 aggregates. Penetrates the blood-brain barrier. . Used for : amyloid- detection in vitro , tissue and in vivo . Shown to bind to plaques in APP-PS1 transgenic mice, in vitro . Detects senile plaques in 19-month-old Tg2576 mice in vivo . . Application : Fluorescence microscopy, epifluorescence microscopy. . Properties and Photophysical Data : CRANAD 2 binds to A 40 aggregates (Kd = 38 nM) and elicits upon interacting with A aggregates, an emission blue shift (from 805 nm to 715 nm). When unbound in PBS, excitation and emission maxima ( ) are 640 nm and 805 nm, respectively.

Near-infrared probe that detects A 40 aggregates

Near-infrared probe that detects A 40 aggregates. Used for: amyloid- detection in vitro and in vivo. Application: fluorescence microscopy, epifluorescence microscopy

(T-4)-[(1E,6E)-1,7-Bis[4-(dimethylamino)phenyl]-1,6-heptadiene-3,5-dionato-kO3,kO5]difluoroboron

C23H25BF2N2O2

C23H25BF2N2O2

1193447-34-5

346 USD

Near-infrared probe that detects A 40 aggregates. Used for: amyloid- detection in vitro and in vivo. Application: fluorescence microscopy, epifluorescence microscopy

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