QNZ 46 | Tocris Bioscience 4801/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

QNZ 46

catalog :

4801/10

quantity :

10 mg (also 50 mg)

price :

245 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Tognatta R, Karl M, Fyffe Maricich S, Popratiloff A, Garrison E, Schenck J, et al. Astrocytes Are Required for Oligodendrocyte Survival and Maintenance of Myelin Compaction and Integrity. Front Cell Neurosci. 2020;14:74 pubmed publisher
Brancaccio M, Patton A, Chesham J, Maywood E, Hastings M. Astrocytes Control Circadian Timekeeping in the Suprachiasmatic Nucleus via Glutamatergic Signaling. Neuron. 2017;93:1420-1435.e5 pubmed publisher

product information

brand :

Tocris

catalog number base :

4801

SKU :

4801/10

product name :

QNZ 46

units size :

10 mg (also 50 mg)

description :

Non-competitive and GluN2C/GluN2D-selective NMDA antagonist

target :

NMDA Receptor Antagonists

category :

Small Molecules

purity :

98%

observed molecular weight :

443.41

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

QNZ 46 is a GluN2C/GluN2D-selective NMDA receptor non-competitive antagonist (IC50 values are 3, 6, 229, and 300, 300 M for GluN2D, GluN2C, GluN2A, GluN2B, and GluR1, respectively). Requires binding of glutamate to the GluN2 subunit. . Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions .

top caption :

Non-competitive and GluN2C/GluN2D-selective NMDA antagonist

extended description :

Non-competitive and GluN2C/GluN2D-selective NMDA antagonist

chemical name text :

4-[6-Methoxy-2-[(1E)-2-(3-nitrophenyl)ethenyl]-4-oxo-3(4H)quinazolinyl]benzoic acid

formula :

C24H17N3O6

formula text :

C24H17N3O6

cas num :

1237744-13-6

USD :

245 USD

product details :

Non-competitive and GluN2C/GluN2D-selective NMDA antagonist

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage