Galloflavin | Tocris Bioscience 4795/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Galloflavin

catalog :

4795/10

quantity :

10 mg

price :

214 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Kottakis F, Nicolay B, Roumane A, Karnik R, Gu H, Nagle J, et al. LKB1 loss links serine metabolism to DNA methylation and tumorigenesis. Nature. 2016;539:390-395 pubmed publisher

product information

brand :

Tocris

master code :

4795

SKU :

4795/10

rank :

0.061

product name :

Galloflavin

description :

Lactate dehydrogenase inhibitor; impairs aerobic glycolysis

target :

Lactate Dehydrogenase A/LDHA Inhibitors

category :

Small Molecules

sizes available :

10 mg

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Galloflavin is an inhibitor of human lactate dehydrogenase (LDH) (Ki values are 5.46 and 15.1 M for LDH-A and LDH-B, respectively, in competition with pyruvate). Inhibits lactate production and decreases ATP synthesis in PLD/PRF/5 cells; thought to decrease cell viability via impairment of aerobic glycolysis.

extended description :

Lactate dehydrogenase inhibitor; impairs aerobic glycolysis

chemical name text :

3,8,9,10-Tetrahydroxypyrano[3,2-c][2]benzopyran-2,6-dione potassium salt

formula :

C 12 H 5 O 8 K

formula text :

C12H5O8K

cas num :

1780260-20-9

USD :

214 USD

product details :

Lactate dehydrogenase inhibitor; impairs aerobic glycolysis

storage :

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage