product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
CE3F4
catalog :
4793
quantity :
10 mg (also 50 mg)
price :
149 USD
more info or order :
citations: 2
Reference
Jakobsen E, Lange S, Bak L. Soluble adenylyl cyclase-mediated cAMP signaling and the putative role of PKA and EPAC in cerebral mitochondrial function. J Neurosci Res. 2019;97:1018-1038 pubmed publisher
Laurent A, Bisserier M, Lucas A, Tortosa F, Roumieux M, De Régibus A, et al. Exchange protein directly activated by cAMP 1 promotes autophagy during cardiomyocyte hypertrophy. Cardiovasc Res. 2015;105:55-64 pubmed publisher
product information
brand :
Tocris
master code :
4793
SKU :
4793/10
product name :
CE3F4
description :
Noncompetitive Epac1 inhibitor
target :
EPAC Inhibitors
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
98%
observed molecular weight :
351.01
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Noncompetitive Epac1 inhibitor. Blocks Epac-induced Rap activation and prevents isoprenaline -induced autophagy flux in cardiomyocytes. Has no effect on PKA activity in the presence of cAMP.
catalog number base :
4793
product keywords :
noncompetitive Epac1 inhibitors inhibits autophagy Exchange proteins Rap guanine nucleotide exchange factor 3 RAPGEF3 cAMP GEFI EPAC 4793,
extended description :
Noncompetitive Epac1 inhibitor
chemical name text :
5,7-Dibromo-6-fluoro-3,4-dihydro-2-methyl-1(2H)-quinolinecarboxaldehyde
formula :
C 11 H 10 Br 2 FNO
formula text :
C11H10Br2FNO
cas num :
143703-25-7
2020 USD :
144
2021 USD :
149 USD
storage :
Store at -20°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK