CE3F4 | Tocris Bioscience 4793/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

CE3F4

catalog :

4793/10

quantity :

10 mg (also 50 mg)

price :

188 USD

citations: 4

Reference
Goode D, Molliver D. Regulation of Mitochondrial Function by Epac2 Contributes to Acute Inflammatory Hyperalgesia. J Neurosci. 2021;41:2883-2898 pubmed publisher
Lee J, Zhang J, Chung Y, Kim J, Kook C, Gonzalez Navajas J, et al. Inhibition of IRF4 in dendritic cells by PRR-independent and -dependent signals inhibit Th2 and promote Th17 responses. elife. 2020;9: pubmed publisher
Jakobsen E, Lange S, Bak L. Soluble adenylyl cyclase-mediated cAMP signaling and the putative role of PKA and EPAC in cerebral mitochondrial function. J Neurosci Res. 2019;97:1018-1038 pubmed publisher
Laurent A, Bisserier M, Lucas A, Tortosa F, Roumieux M, De RÃ©gibus A, et al. Exchange protein directly activated by cAMP 1 promotes autophagy during cardiomyocyte hypertrophy. Cardiovasc Res. 2015;105:55-64 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

4793

SKU :

4793/10

product name :

CE3F4

description :

Noncompetitive Epac1 inhibitor

target :

EPAC Inhibitors

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

351.01

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

CE3F4 is a noncompetitive Epac1 inhibitor. Blocks Epac-induced Rap activation and prevents isoprenaline -induced autophagy flux in cardiomyocytes. Has no effect on PKA activity in the presence of cAMP.

product keywords :

noncompetitive Epac1 inhibitors inhibits autophagy Exchange proteins Rap guanine nucleotide exchange factor 3 RAPGEF3 cAMP GEFI EPAC 4793,

extended description :

Noncompetitive Epac1 inhibitor

chemical name text :

5,7-Dibromo-6-fluoro-3,4-dihydro-2-methyl-1(2H)-quinolinecarboxaldehyde

formula :

C11H10Br2FNO

formula text :

C11H10Br2FNO

cas num :

143703-25-7

USD :

186

USD 2025 :

188 USD

product details :

Noncompetitive Epac1 inhibitor