Candesartan | Tocris Bioscience 4791/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Candesartan

catalog :

4791/10

quantity :

10 mg (also 50 mg)

price :

96 USD

citations: 4

Reference
Labandeira C, Pedrosa M, Quijano A, Valenzuela R, Garrido Gil P, Sanchez Andrade M, et al. Angiotensin type-1 receptor and ACE2 autoantibodies in Parkinson´s disease. NPJ Parkinsons Dis. 2022;8:76 pubmed publisher
Quijano A, Díaz Ruiz C, López López A, Villar Cheda B, Mu xf1 oz A, Rodriguez Perez A, et al. Angiotensin Type-1 Receptor Inhibition Reduces NLRP3 Inflammasome Upregulation Induced by Aging and Neurodegeneration in the Substantia Nigra of Male Rodents and Primary Mesencephalic Cultures. Antioxidants (Basel). 2022;11: pubmed publisher
Attilio P, Snapper D, Rusnak M, Isaac A, Soltis A, Wilkerson M, et al. Transcriptomic Analysis of Mouse Brain After Traumatic Brain Injury Reveals That the Angiotensin Receptor Blocker Candesartan Acts Through Novel Pathways. Front Neurosci. 2021;15:636259 pubmed publisher
Pedrosa M, Valenzuela R, Garrido Gil P, Labandeira C, Navarro G, Franco R, et al. Experimental data using candesartan and captopril indicate no double-edged sword effect in COVID-19. Clin Sci (Lond). 2021;135:465-481 pubmed publisher

product information

brand :

Tocris

master code :

4791

SKU :

4791/10

product name :

Candesartan

unit size :

10 mg (also 50 mg)

seo description :

AT1 antagonist

target :

Angiotensin AT1 Receptor Antagonists

category :

Small Molecules

purity :

98%

observed molecular weight :

440.45

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Candesartan is an angiotensin II receptor 1 (AT1) antagonist (IC50 values are 1.12 and 2.86 nM in bovine adrenal cortex and rabbit aorta, respectively). Exhibits antihypertensive effects in animal models. Also available as a prodrug, candesartan cilexetil (Cat. No. 4792).

top caption :

AT1 antagonist

extended description :

AT1 antagonist

chemical name text :

2-Ethoxy-1-[[2 -(1H-tetrazol-5-yl)[1,1 -biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic acid

formula :

C24H20N6O3

formula text :

C24H20N6O3

cas num :

139481-59-7

USD :

96 USD

product details :

AT1 antagonist

alt names :

CV 11974

storage :

Store at RT