Org 25543 hydrochloride | Tocris Bioscience 4782 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Org 25543 hydrochloride

catalog :

4782

quantity :

10 mg (also 50 mg)

price :

227 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Morita K, Motoyama N, Kitayama T, Morioka N, Kifune K, Dohi T. Spinal antiallodynia action of glycine transporter inhibitors in neuropathic pain models in mice. J Pharmacol Exp Ther. 2008;326:633-45 pubmed publisher

product information

brand :

Tocris

master code :

4782

SKU :

4782/10

product name :

Org 25543 hydrochloride

description :

Potent and selective GlyT2 inhibitor

target :

Glycine Transporter Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

448.98

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective glycine transporter type 2 (GlyT2) inhibitor (IC50 = 16 nM for hGlyT2). Displays no activity at GlyT1 or 56 other common biological targets ( 100 M), in a glycine uptake assay in CHO cells. Ameliorates mechanical allodynia after partial sciatic nerve ligation injury in mice.

catalog number base :

4782

product keywords :

Org25543 hydrochloride glycine transporter type-2 GlyT-2 GlyT2 inhibitors inhibits allodynia pain neuropathic Glycine Transporters 4782,

extended description :

Potent and selective GlyT2 inhibitor

chemical name text :

N-[[1-(Dimethylamino)cyclopentyl]methyl]-3,5-dimethoxy-4-(phenylmethoxy)benzamide hydrochloride

formula :

C 24 H 32 lN 2 O 4 .HCl

formula text :

C24H32lN2O4.HCl

cas num :

495076-64-7

2020 USD :

218

2021 USD :

227 USD

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage