GRI 977143 | Tocris Bioscience 4779/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

GRI 977143

catalog :

4779/10

quantity :

10 mg (also 50 mg)

price :

246 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

4779

SKU :

4779/10

rank :

0.061

product name :

GRI 977143

description :

Selective LPA2 receptor non-lipid agonist

target :

Lysophosphatidic Acid (LPA) Receptor Agonists

category :

Small Molecules

sizes available :

10 mg (also 50 mg)

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

GRI 977143 is a selective lysophosphatidic acid 2 (LPA2) receptor non-lipid agonist (EC50 = 3.3 M). Does not activate other LPA GPCRs at concentrations up to 10 M. Antiapoptotic; inhibits activation of caspases 3, 7, 8 and 9, Bax translocation and PARP-1 cleavage. Activates ERK1/2 survival pathway.

extended description :

Selective LPA2 receptor non-lipid agonist

chemical name text :

2-[[3-(1,3-dioxo-1H-benz[de]isoquinolin-2(3H)-yl)propyl]thio]benzoic acid

formula :

C 22 H 17 NO 4 S

formula text :

C22H17NO4S

cas num :

325850-81-5

USD :

246 USD

product details :

Selective LPA2 receptor non-lipid agonist

storage :

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage