ML 277 | Tocris Bioscience 4777/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ML 277

catalog :

4777/10

quantity :

10 mg (also 50 mg)

price :

262 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 4777 - ML 277 C23H25N3O4S2 CAS No. 1401242-74-7

product information

brand :

Tocris

master code :

4777

SKU :

4777/10

rank :

0.061

product name :

ML 277

description :

Selective KV7.1 (KCNQ1) potassium channel activator; augments IKs current

target :

Voltage-gated Potassium Channel Activators

category :

Small Molecules

sizes available :

10 mg (also 50 mg)

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

ML 277 is a selective Kv7.1 (KCNQ1) potassium channel activator (EC50 = 260 nM). Exhibits 100-fold selectivity versus KCNQ2, KCNQ4 and hERG potassium channels. Augments IKs current of cultured human cardiomyocytes and shortens action potential duration.

extended description :

Selective KV7.1 (KCNQ1) potassium channel activator; augments IKs current

chemical name text :

(2R)-N-[4-(4-Methoxyphenyl)-2-thiazolyl]-1-[(4-methylphenyl)sulfonyl]-2-piperidinecarboxamide

formula :

C 23 H 25 N 3 O 4 S 2

formula text :

C23H25N3O4S2

cas num :

1401242-74-7

USD :

262 USD

product details :

Selective KV7.1 (KCNQ1) potassium channel activator; augments IKs current

storage :

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage