ESI 09 | Tocris Bioscience 4773 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ESI 09

catalog :

4773

quantity :

10 mg (also 50 mg)

price :

195 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
Perkins D, Richard K, Hansen A, Lai W, Nallar S, Koller B, et al. Autocrine-paracrine prostaglandin E2 signaling restricts TLR4 internalization and TRIF signaling. Nat Immunol. 2018;19:1309-1318 pubmed publisher
Drelich A, Judy B, He X, Chang Q, Yu S, Li X, et al. Exchange Protein Directly Activated by cAMP Modulates Ebola Virus Uptake into Vascular Endothelial Cells. Viruses. 2018;10: pubmed publisher
Guichard A, Jain P, Moayeri M, Schwartz R, Chin S, Zhu L, et al. Anthrax edema toxin disrupts distinct steps in Rab11-dependent junctional transport. PLoS Pathog. 2017;13:e1006603 pubmed publisher
Wang J, Cao Y, Li Q, Yang Y, Jin M, Chen D, et al. A pivotal role of FOS-mediated BECN1/Beclin 1 upregulation in dopamine D2 and D3 receptor agonist-induced autophagy activation. Autophagy. 2015;11:2057-2073 pubmed publisher

product information

brand :

Tocris

master code :

4773

SKU :

4773/10

product name :

ESI 09

description :

Epac inhibitor

target :

EPAC Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

330.77

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

EPAC inhibitor. Inhibits EPAC-mediated insulin releases from pancreatic cells. Selective for EPAC over PKA. Decreases migration and invasion of AsPc-1 and PANC-1 pancreatic cancer cells in vitro .

catalog number base :

4773

product keywords :

ESI09 EPAC exchange proteins inhibitors inhibits GTPases Rap guanine nucleotide exchange factor cAMP GEFI EPAC 4773,

extended description :

Epac inhibitor

chemical name text :

-[(2-(3-Chlorophenyl)hydrazinylidene]-5-(1,1-dimethylethyl)- -oxo-3-isoxazolepropanenitrile

formula :

C 16 H 15 ClN 4 O 2

formula text :

C16H15ClN4O2

cas num :

263707-16-0

2020 USD :

187

2021 USD :

195 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage