Pyridostatin pentahydrochloride | Tocris Bioscience 4763/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Pyridostatin pentahydrochloride

catalog :

4763/10

quantity :

10 mg

price :

270 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

4763

SKU :

4763/10

rank :

0.061

product name :

Pyridostatin pentahydrochloride

description :

Stabilizes G-quadruplexes; induces DNA damage and cell cycle arrest

target :

Cell Cycle Inhibitors

category :

Small Molecules

sizes available :

10 mg

url print :

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details of functionality :

Binds and stabilizes G-quadruplexes, inducing DNA damage and cell cycle arrest (Kd = 490 nM); targets the proto-oncogene Src, reducing Src protein abundance and Src-dependent motility in human breast cancer cells. Also targets telomeric G-quadruplexes, inducing telomerase dysfunction. Activates the DNA-dependent protein kinase catalytic sunbunit (DNA-PKcs).

extended description :

Stabilizes G-quadruplexes; induces DNA damage and cell cycle arrest

chemical name text :

4-(2-Aminoethoxy)N2,N6-bis[(4-(2-aminoethoxy)-2-quinolinyl]-2,6-pyridinecarboxamide pentahydrochloride

formula :

C 31 H 32 N 8 O 5 .5HCl

formula text :

C31H32N8O5.5HCl

cas num :

1781882-65-2

USD :

270 USD

product details :

Stabilizes G-quadruplexes; induces DNA damage and cell cycle arrest

storage :

Store the unopened product at room temperature. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage