AK 7 | Tocris Bioscience 4754/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

AK 7

catalog :

4754/10

quantity :

10 mg (also 50 mg)

price :

188 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

4754

SKU :

4754/10

rank :

0.061

product name :

AK 7

description :

Selective SIRT2 inhibitor; brain penetrant

target :

Class III Histone Deacetylases Inhibitors

category :

Small Molecules

sizes available :

10 mg (also 50 mg)

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

AK 7 is a selective SIRT2 inhibitor (IC50 = 15.5 M); displays no effect on SIRT1 or SIRT3. Decreases neuronal cholesterol levels; improves motor function and ameliorates brain atrophy in a mouse model of Huntington s disease. Brain penetrant.

extended description :

Selective SIRT2 inhibitor; brain penetrant

chemical name text :

N-(3-Bromophenyl)-3-[(hexahydro-1H-azepin-1-yl)sulfonyl]benzamide

formula :

C 19 H 21 BrN 2 O 3 S

formula text :

C19H21BrN2O3S

cas num :

420831-40-9

USD :

188 USD

product details :

Selective SIRT2 inhibitor; brain penetrant

storage :

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage