FSLLRY-NH2 | Tocris Bioscience 4751 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

FSLLRY-NH2

catalog :

4751

quantity :

1 mg

price :

108 USD

more info or order :

Tocris Bioscience product webpage

citations: 6

Reference
Noskovičová N, Heinzelmann K, Burgstaller G, Behr J, Eickelberg O. Cub domain-containing protein 1 negatively regulates TGF-β signaling and myofibroblast differentiation. Am J Physiol Lung Cell Mol Physiol. 2018;314:L695-L707 pubmed publisher
Peng S, Gerasimenko J, Tsugorka T, Gryshchenko O, Samarasinghe S, Petersen O, et al. Calcium and adenosine triphosphate control of cellular pathology: asparaginase-induced pancreatitis elicited via protease-activated receptor 2. Philos Trans R Soc Lond B Biol Sci. 2016;371: pubmed publisher
White M, Galvis Carvajal E, Gomer R. A brief exposure to tryptase or thrombin potentiates fibrocyte differentiation in the presence of serum or serum amyloid p. J Immunol. 2015;194:142-50 pubmed publisher
Bao Y, Hou W, Liu R, Gao Y, Kong X, Yang L, et al. PAR2-mediated upregulation of BDNF contributes to central sensitization in bone cancer pain. Mol Pain. 2014;10:28 pubmed publisher
Tripathi T, Abdi M, Alizadeh H. Protease-activated receptor 2 (PAR2) is upregulated by Acanthamoeba plasminogen activator (aPA) and induces proinflammatory cytokine in human corneal epithelial cells. Invest Ophthalmol Vis Sci. 2014;55:3912-21 pubmed publisher
Eum S, Jaraki D, Bertrand L, Andras I, Toborek M. Disruption of epithelial barrier by quorum-sensing N-3-(oxododecanoyl)-homoserine lactone is mediated by matrix metalloproteinases. Am J Physiol Gastrointest Liver Physiol. 2014;306:G992-G1001 pubmed publisher

product information

brand :

Tocris

master code :

4751

SKU :

4751/1

product name :

FSLLRY-NH2

description :

PAR2 peptide antagonist

target :

Protease-Activated Receptor Antagonists

category :

Peptides

unit size :

1 mg

observed molecular weight :

796.97

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

Selective PAR2 peptide antagonist. Reverses taxol -induced mechanical allodynia, heat hyperalgesia and PKC activation in ICR mice. Blocks ERK activation and collagen production in isolated cardiac fibroblasts. Also reduces symptoms in a mouse model of dermatophyte-associated itch.

catalog number base :

4751

product keywords :

PAR2 protease activated receptors selective antagonists Protease-Activated Receptors 4751,

extended description :

PAR2 peptide antagonist

formula :

C 39 H 60 N 10 O 8

formula text :

C39H60N10O8

cas num :

245329-02-6

2020 USD :

103

2021 USD :

108 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage