product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
FSLLRY-NH2
catalog :
4751/1
quantity :
1 mg
price :
126 USD
more info or order :
citations: 6
Reference
Noskovičová N, Heinzelmann K, Burgstaller G, Behr J, Eickelberg O. Cub domain-containing protein 1 negatively regulates TGF-β signaling and myofibroblast differentiation. Am J Physiol Lung Cell Mol Physiol. 2018;314:L695-L707 pubmed publisher
Peng S, Gerasimenko J, Tsugorka T, Gryshchenko O, Samarasinghe S, Petersen O, et al. Calcium and adenosine triphosphate control of cellular pathology: asparaginase-induced pancreatitis elicited via protease-activated receptor 2. Philos Trans R Soc Lond B Biol Sci. 2016;371: pubmed publisher
White M, Galvis Carvajal E, Gomer R. A brief exposure to tryptase or thrombin potentiates fibrocyte differentiation in the presence of serum or serum amyloid p. J Immunol. 2015;194:142-50 pubmed publisher
Bao Y, Hou W, Liu R, Gao Y, Kong X, Yang L, et al. PAR2-mediated upregulation of BDNF contributes to central sensitization in bone cancer pain. Mol Pain. 2014;10:28 pubmed publisher
Tripathi T, Abdi M, Alizadeh H. Protease-activated receptor 2 (PAR2) is upregulated by Acanthamoeba plasminogen activator (aPA) and induces proinflammatory cytokine in human corneal epithelial cells. Invest Ophthalmol Vis Sci. 2014;55:3912-21 pubmed publisher
Eum S, Jaraki D, Bertrand L, Andras I, Toborek M. Disruption of epithelial barrier by quorum-sensing N-3-(oxododecanoyl)-homoserine lactone is mediated by matrix metalloproteinases. Am J Physiol Gastrointest Liver Physiol. 2014;306:G992-G1001 pubmed publisher
product information
brand :
Tocris
master code :
4751
SKU :
4751/1
rank :
0.061
product name :
FSLLRY-NH2
description :
PAR2 peptide antagonist
target :
Protease-Activated Receptor Antagonists
category :
Peptides
sizes available :
1 mg
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=peptides
details of functionality :
FSLLRY-NH2 is a selective PAR2 peptide antagonist. Reverses taxol -induced mechanical allodynia, heat hyperalgesia and PKC activation in ICR mice. Blocks ERK activation and collagen production in isolated cardiac fibroblasts. Also reduces symptoms in a mouse model of dermatophyte-associated itch.
extended description :
PAR2 peptide antagonist
formula :
C 39 H 60 N 10 O 8
formula text :
C39H60N10O8
cas num :
245329-02-6
USD :
126 USD
product details :
PAR2 peptide antagonist
storage :
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK