FSLLRY-NH2 | Tocris Bioscience 4751/1 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

FSLLRY-NH2

catalog :

4751/1

quantity :

1 mg

price :

137 USD

more info or order :

Tocris Bioscience product webpage

citations: 10

Reference
Kumar R, Rojas I, Edgerton M. Candida albicans Sap6 Initiates Oral Mucosal Inflammation via the Protease Activated Receptor PAR2. Front Immunol. 2022;13:912748 pubmed publisher
Carey R, Freund J, Hariri B, Adappa N, Palmer J, Lee R. Polarization of protease-activated receptor 2 (PAR-2) signaling is altered during airway epithelial remodeling and deciliation. J Biol Chem. 2020;295:6721-6740 pubmed publisher
Gordon E, Yao X, Xu H, Karkowsky W, Kaler M, Kalchiem Dekel O, et al. Apolipoprotein E is a concentration-dependent pulmonary danger signal that activates the NLRP3 inflammasome and IL-1β secretion by bronchoalveolar fluid macrophages from asthmatic subjects. J Allergy Clin Immunol. 2019;: pubmed publisher
Noskovičová N, Heinzelmann K, Burgstaller G, Behr J, Eickelberg O. Cub domain-containing protein 1 negatively regulates TGF-β signaling and myofibroblast differentiation. Am J Physiol Lung Cell Mol Physiol. 2018;314:L695-L707 pubmed publisher
Toyama S, Okada N, Matsuda A, Morita H, Saito H, Fujisawa T, et al. Human eosinophils constitutively express a unique serine protease, PRSS33. Allergol Int. 2017;66:463-471 pubmed publisher
Peng S, Gerasimenko J, Tsugorka T, Gryshchenko O, Samarasinghe S, Petersen O, et al. Calcium and adenosine triphosphate control of cellular pathology: asparaginase-induced pancreatitis elicited via protease-activated receptor 2. Philos Trans R Soc Lond B Biol Sci. 2016;371: pubmed publisher
White M, Galvis Carvajal E, Gomer R. A brief exposure to tryptase or thrombin potentiates fibrocyte differentiation in the presence of serum or serum amyloid p. J Immunol. 2015;194:142-50 pubmed publisher
Bao Y, Hou W, Liu R, Gao Y, Kong X, Yang L, et al. PAR2-mediated upregulation of BDNF contributes to central sensitization in bone cancer pain. Mol Pain. 2014;10:28 pubmed publisher
Tripathi T, Abdi M, Alizadeh H. Protease-activated receptor 2 (PAR2) is upregulated by Acanthamoeba plasminogen activator (aPA) and induces proinflammatory cytokine in human corneal epithelial cells. Invest Ophthalmol Vis Sci. 2014;55:3912-21 pubmed publisher
Eum S, Jaraki D, Bertrand L, Andras I, Toborek M. Disruption of epithelial barrier by quorum-sensing N-3-(oxododecanoyl)-homoserine lactone is mediated by matrix metalloproteinases. Am J Physiol Gastrointest Liver Physiol. 2014;306:G992-G1001 pubmed publisher

product information

brand :

Tocris

catalog number base :

4751

SKU :

4751/1

product name :

FSLLRY-NH2

units size :

1 mg

description :

PAR2 peptide antagonist

target :

Protease-Activated Receptor Antagonists

category :

Peptides

purity :

95%

observed molecular weight :

796.97

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

FSLLRY-NH2 is a selective PAR2 peptide antagonist. Reverses taxol -induced mechanical allodynia, heat hyperalgesia and PKC activation in ICR mice. Blocks ERK activation and collagen production in isolated cardiac fibroblasts. Also reduces symptoms in a mouse model of dermatophyte-associated itch. FSLLRY-NH2 inhibits C. albicans induced inflammation in oral mucosal cells in vitro .

top caption :

PAR2 peptide antagonist

extended description :

PAR2 peptide antagonist

formula :

C39H60N10O8

formula text :

C39H60N10O8

cas num :

245329-02-6

USD :

137 USD

product details :

PAR2 peptide antagonist

storage :

Store at -20Â°C

more info or order :

Tocris Bioscience product webpage