TC Mps1 12 | Tocris Bioscience 4750/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TC Mps1 12

catalog :

4750/10

quantity :

10 mg (also 50 mg)

price :

217 USD

citations: 1

Reference
Choi M, Min Y, Pyo J, Lee C, Jang C, Kim J. TC Mps1 12, a novel Mps1 inhibitor, suppresses the growth of hepatocellular carcinoma cells via the accumulation of chromosomal instability. Br J Pharmacol. 2017;174:1810-1825 pubmed publisher

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

4750

SKU :

4750/10

product name :

TC Mps1 12

Description :

Potent and selective Mps1 kinase inhibitor

target :

TTK/Mps1 Kinase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

324.38

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

TC Mps1 12 is a potent and selective monopolar spindle 1 (Mps1) inhibitor (IC50 = 6.4 nM). Selective for Mps1 over a panel of 95 kinases including JNK. Inhibits A549 lung carcinoma cell proliferation and attenuates A549 cell xenograft growth in mice. Orally active.

extended description :

Potent and selective Mps1 kinase inhibitor

chemical name text :

4-[[4-Amino-5-cyano-6-[(1,1-dimethylethyl)amino]-2-pyridinyl]amino]benzamide

formula :

C 17 H 20 N 6 O

cas num :

1206170-62-8

USD :

217 USD

product details :

Potent and selective Mps1 kinase inhibitor

storage :

Store at +4°C