ML SA1 | Tocris Bioscience 4746 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ML SA1

catalog :

4746

quantity :

10 mg (also 50 mg)

price :

119 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Fine M, Schmiege P, Li X. Structural basis for PtdInsP2-mediated human TRPML1 regulation. Nat Commun. 2018;9:4192 pubmed publisher

product information

brand :

Tocris

master code :

4746

SKU :

4746/10

product name :

ML SA1

description :

Activator of TRPML channels

target :

TRPML Channel Activators

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

362.42

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Activator of TRPML channels (TRPML1, 2 and 3); does not activate TRPM2, TRPV2, TRPV3, TRPC6 or TRPA1 channels. Induces TRPML-mediated Ca2+ release from lysosomes; activity corrects trafficking defects and reduces cholesterol accumulation in Niemann-Pick type C macrophages.

catalog number base :

4746

product keywords :

MLSA1 trpml transient receptor potential channels mucolipin TRPML1 TRPML2 TRPML3 lysosomal lysosome storage diseases TRPML 4746,

extended description :

Activator of TRPML channels

chemical name text :

2-[2-(3,4-Dihydro-2,2,4-trimethyl-1(2H)-quinolinyl)-2-oxoethyl]-1H-isoindole-1,3(2H)-dione

formula :

C 22 H 22 N 2 O 3

formula text :

C22H22N2O3

cas num :

332382-54-4

2020 USD :

114

2021 USD :

119 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage