product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
KY 02111
catalog :
4731
quantity :
25 mg
price :
309 USD
more info or order :
citations: 1
Reference
Qiu X, Liu Y, Zhang Y, Guan Y, Jia Q, Wang C, et al. Rapamycin and CHIR99021 Coordinate Robust Cardiomyocyte Differentiation From Human Pluripotent Stem Cells Via Reducing p53-Dependent Apoptosis. J Am Heart Assoc. 2017;6: pubmed publisher
product information
brand :
Tocris
master code :
4731
SKU :
4731/25
product name :
KY 02111
description :
Inhibits canonical Wnt signaling. Promotes differentiation of human ESCs and iPSCs into cardiomyocytes
target :
Compounds for Stem Cell Differentiation
category :
Small Molecules
unit size :
25 mg
purity :
99%
observed molecular weight :
376.86
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Promotes differentiation of human ESCs and iPSCs into cardiomyocytes when used after day three in culture; differentiation efficiency increases when used after initial culture with CHIR 99021 (Cat. No. 4423). Induces downregulation of Wnt signaling target genes; inhibits canonical Wnt signaling in a manner distinct from other known Wnt inhibitors.
catalog number base :
4731
product keywords :
KY02111 stem cell differentiation cardiomyocytes human iPSCs ESCs Wnt signaling pathway inhibits inhibitors Other Wnt Signaling Cardiomyocyte Stem Cells ESCs and iPSC 4731, differentiation stem cells, DIFFERENTIATION STEM CELLS
extended description :
Inhibits canonical Wnt signaling. Promotes differentiation of human ESCs and iPSCs into cardiomyocytes
chemical name text :
N-(6-Chloro-2-benzothiazolyl)-3,4-dimethoxybenzenepropanamide
formula :
C 18 H 17 ClN 2 O 3 S
formula text :
C18H17ClN2O3S
cas num :
1118807-13-8
2020 USD :
297
2021 USD :
309 USD
storage :
Store at +4°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK