CTA 056 | Tocris Bioscience 4726 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

CTA 056

catalog :

4726

quantity :

2 mg

price :

79 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Mues M, Karra L, Romero Moya D, Wandler A, Hangauer M, Ksionda O, et al. High-Complexity shRNA Libraries and PI3 Kinase Inhibition in Cancer: High-Fidelity Synthetic Lethality Predictions. Cell Rep. 2019;27:631-647.e5 pubmed publisher

image

image 1 :

Cat.No. 4726 - CTA 056 CAS No. 1265822-30-7

product information

brand :

Tocris

master code :

4726

SKU :

4726/2

product name :

CTA 056

description :

ITK inhibitor

target :

ITK Inhibitors

category :

Small Molecules

unit size :

2 mg

purity :

98%

observed molecular weight :

554.68

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Interleukin-2-inducible T-cell kinase (ITK) inhibitor (IC50 values are 0.1, 0.4 and 5 M for ITK, BTK and ETK, respectively). Inhibits growth of cancer cells expressing ITK, including MOLT-4 and Jurkat cells in vitro . Induces apoptosis in Jurkat cells. Inhibits MOLT-4 xenograft tumor growth in mice.

catalog number base :

4726

product keywords :

CTA056 cancer apoptosis interleukin 2 inducible T-cell kinase Itk inhibitors inhibits induces inducers ITK 4726,

extended description :

ITK inhibitor

chemical name text :

1,5-Dihydro-7-(phenylmethyl)-1-[3-(1-piperidinyl)propyl]-2-[4-(4-pyridinyl)phenyl]-6H-imidazo[4,5-g]quinoxalin-6-one

formula :

C 35 H 34 N 6 O

cas num :

1265822-30-7

2020 USD :

2021 USD :

79 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage