product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
CTA 056
catalog :
4726/2
quantity :
2 mg
price :
90 USD
more info or order :
citations: 1
Reference
Mues M, Karra L, Romero Moya D, Wandler A, Hangauer M, Ksionda O, et al. High-Complexity shRNA Libraries and PI3 Kinase Inhibition in Cancer: High-Fidelity Synthetic Lethality Predictions. Cell Rep. 2019;27:631-647.e5 pubmed publisher
image
image 1 :
Tocris Bioscience 4726/2 image 1
Cat.No. 4726 - CTA 056 CAS No. 1265822-30-7
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
4726
SKU :
4726/2
product name :
CTA 056
description :
ITK inhibitor
target :
ITK Inhibitors
unit size :
2 mg
category :
Small Molecules
purity :
98%
storage :
Store at -20°C
observed molecular weight :
554.68
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
CTA 056 is an interleukin-2-inducible T-cell kinase (ITK) inhibitor (IC50 values are 0.1, 0.4 and 5 M for ITK, BTK and ETK, respectively). Inhibits growth of cancer cells expressing ITK, including MOLT-4 and Jurkat cells in vitro . Induces apoptosis in Jurkat cells. Inhibits MOLT-4 xenograft tumor growth in mice.
product keywords :
CTA056 cancer apoptosis interleukin 2 inducible T-cell kinase Itk inhibitors inhibits induces inducers ITK 4726,
extended description :
ITK inhibitor
chemical name text :
1,5-Dihydro-7-(phenylmethyl)-1-[3-(1-piperidinyl)propyl]-2-[4-(4-pyridinyl)phenyl]-6H-imidazo[4,5-g]quinoxalin-6-one
formula :
C35H34N6O
cas num :
1265822-30-7
USD :
99
USD 2025 :
90 USD
product details :
ITK inhibitor
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK