Entacapone | Tocris Bioscience 4720/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Entacapone

catalog :

4720/10

quantity :

10 mg (also 50 mg)

price :

74 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

4720

SKU :

4720/10

rank :

0.061

product name :

Entacapone

description :

Potent COMT inhibitor; blocks -synuclein aggregation

target :

Catechol O-Methyltransferase (COMT) Inhibitors

category :

Small Molecules

sizes available :

10 mg (also 50 mg)

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Entacapone is a potent catechol O -methyltransferase (COMT) inhibitor (IC50 values are 14.3, 20.1 and 73.3 nM for rat liver soluble COMT, total COMT and membrane-bound COMT respectively). Increases bioavailability of levodopa when given as an adjunct therapy for Parkinson s disease. Inhibits -synuclein aggregation in an in vitro assay; blocks -synuclein-induced cell death in PC-12 cells.

extended description :

Potent COMT inhibitor; blocks -synuclein aggregation

chemical name text :

(2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide

formula :

C 14 H 15 N 3 O 5

formula text :

C14H15N3O5

cas num :

130929-57-6

USD :

74 USD

product details :

Potent COMT inhibitor; blocks -synuclein aggregation

storage :

Store the unopened product at room temperature. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage